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Insulin resistance and the causes

insulin resistance

Insulin is a hormone produced by the pancreas that allows cells to use glucose (sugar) for energy.

People with insulin resistance have cells that do not use insulin effectively, which means that the cells have difficulty absorbing glucose. Decreased ability of cells to respond to the action of insulin in transporting glucose (sugar) into the blood circulation in muscle and other tissues results in an accumulation of glucose in the blood. Therefore, the body needs higher levels of insulin to help glucose get into the cells. The pancreas is trying to keep increasing the demand for insulin by producing more. While it is able to produce enough insulin to overcome insulin resistance, glucose remains in the healthy range.

But over time, the pancreas stops following the increased demand for insulin. Without enough insulin, excess glucose builds up in the bloodstream, leading to pre-diabetes, diabetes and other serious health disorders.

– symptom

Insulin resistance usually has no symptoms. People may have the condition for years without knowing they have it.

People with severe forms may develop dark spots on the skin, usually on the back of the neck. Sometimes people have a black ring around their neck. Dark spots can also appear on the elbows, knees, joints and underarms. Changes in the skin usually occur slowly. The affected skin may also have an itchy smell. This condition is called acanthosis nigricans.

– cause

Although the exact causes are not accurately known, there are some taxpayers as described below – Obesity – Many experts believe that obesity is the leading cause of insulin resistance, especially excess fat around the waist. According to numerous studies, belly fat produces hormones and other substances that can cause serious health problems like insulin resistance, high blood pressure, cholesterol balance and cardiovascular disease (CVD). Belly fat plays a role in the development of chronic inflammation in the body. This inflammation may contribute to the development of insulin resistance, type 2 diabetes and cardiovascular disease. However, studies show that weight loss can reduce insulin resistance and prevent or delay type 2 diabetes.

Physical inactivity – Numerous studies indicate that physical inactivity is also related to insulin resistance. Studies show that after exercise, muscles become more sensitive to insulin, reverse insulin resistance and blood glucose levels. Exercise also helps muscles absorb more glucose without the need for insulin. The more muscle a person has, the more they can burn glucose to control blood glucose levels. Therefore, weight training plays an important role in reverse as it helps the growth of muscles.

Sleep Problems – Many studies show that sleep disorders, especially sleep apnea can increase the risk of obesity, insulin resistance and type 2 diabetes. Night workers may also be at a higher risk of these problems. Sleep problems also lead to poor sleep quality, drowsiness or excessive daytime fatigue.

Other Causes – There are other causes may be ethnicity, certain diseases, hormones, use of steroids, certain medications, age and smoking.

The final result –

It is a disturbing fact that insulin resistance is common throughout the world and its prevalence continues to increase. Another worrying trend was statistically observed that one-third of obese children and adolescents, who are a group at high risk of developing type 2 diabetes and cardiovascular disease. This becomes even more important as the incidence of obesity is increasing among children and adolescents in the world

It is undeniable that type 2 diabetes has reached epidemic proportions worldwide. At the same time, due to the high prevalence of overweight and obesity associated with physical inactivity and poor dietary habits, the tendency to increase insulin resistance in adults and adolescents is very strong. This is a good omen to further aggravate the high prevalence of type 2 diabetes. Therefore, it is required to be marked in time to prevent the situation from getting out of control.


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